Medical Services

Fecal Microbiota Transplantation (FMT)

Fecal Microbiota Transplantation (FMT) is a procedure in which the intestinal microbiota contained in the stool of a healthy donor is transplanted into the intestines of a patient via colonoscopy. It is a medical technology that attempts to treat diseases caused by intestinal imbalance disorders, or dysbiosis.

Inflammatory Bowel Disease (IBD) is one of many diseases that is caused by dysbiosis. The number of patients diagnosed with IBD is said to exceed approximately 200,000 in Japan, which accounts for a large population of patients*1.

In order to effectively implement FMT, it is essential to develop an ‘intestinal microbiome bank’ that connects patients to healthy donors. In collaboration with Juntendo University, Metagen Therapeutics is developing an ‘intestinal microbiome bank’ to facilitate the collection of stool and the preparation of microbiota for use in FMT.

Our Chief Medical Officer, Dr. Ishikawa, is currently conducting clinical research*2 on FMT at Juntendo University.

*1 Ministry of Health, Labour and Welfare Grants for Intractable Disease Policy Research Project (2016). Survey Research on Refractory IBD.

*2 Juntendo University FMT for ulcerative colitis